Sanskruti Pharma

Apalutamide is a medication primarily used in the treatment of prostate cancer. Here's a quick breakdown of what it is and how it works:

What is Apalutamide?

• Brand Name: APNAT

• Drug Class: Androgen receptor inhibitor (anti-androgen)

• Used For:

  • Non-metastatic castration-resistant prostate cancer (nmCRPC)

  • Metastatic castration-sensitive prostate cancer (mCSPC)

⚙️ How It Works:

Apalutamide blocks the action of androgens (male hormones like testosterone) by binding to androgen receptors. Since prostate cancer cells often rely on these hormones to grow, blocking them slows down or stops cancer growth.

How It’s Taken:

• Form: Oral tablet

• Dosage: Typically 240 mg once daily (4 tablets of 60 mg), taken at the same time each day.

• Often combined with: Ongoing androgen deprivation therapy (ADT) or surgical castration.

⚠️ Common Side Effects:

• Fatigue

• Hypertension

• Rash

• Falls and fractures

• Weight loss

• Joint pain

• Hot flashes

 Notes and Warnings:

• Seizure risk: Rare, but caution advised in patients with a history of seizures.

• Monitor thyroid function, liver function, and bone health during treatment.

• Pregnancy category X: Not for use in women, especially during pregnancy.